Cite as: Cold Spring Harb. Protoc.; 2008; doi:10.1101/pdb.prot4805

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The Nissl Stain: A Stain for Cell Bodies in Brain Sections

Carol Ann Paul, Barbara Beltz, and Joanne Berger-Sweeney

Adapted from Discovering Neurons: The Experimental Basis of Neuroscience (eds. Paul et al.). CSHL Press, Cold Spring Harbor, NY, USA, 1997.


INTRODUCTION

The Nissl stain is used widely in many research labs to examine the overall morphology of the brain. It is often used to verify the location of a lesion or an electrode.


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