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Transposable elements (TEs) comprise large fractions of eukaryotic genomes, but their repetitive nature and high copy number makes bioinformatic analyses more complex. In this issue, Teefy et al. describe computational pipelines to analyze TE expression from RNA-seq data in the African turquoise killifish Nothobranchius furzeri (doi:10.1101/pdb.prot107748). The image is an artistic rendition of DNA strands “jumping out” of a pair of killifish, used to represent the nature of transposable elements as “jumping genes.” The image was rendered using the DALL-E AI engine using the prompt “double helix DNA strands jumping out of female and male nothobranchius furzeri digital art dark.” Image courtesy of the authors.