Table 1. Labels and areas of application for single-particle tracking and single-molecule detection

Table

Labels	Latex	Gold	QDs	XFPs	Dyes
Typical applications	Diffusion	Diffusion	Diffusion localization	Localization stoichiometry interactions	Diffusion localization interactions
Size	200-1000 nm	40 nm	10-15 nm	2 × 4 nm	<1 nm
Coupling	Passive or chemical linkage	Passive absorption	Chemical linkage	Genetic fusion	Chemical linkage
Excitation	Halogen lamp	Halogen lamp	Laser light or spectral lamps	Laser light	Laser light
Detection	DIC and videocamera	DIC and videocamera	Low-light-level camera	Low-light-level camera	Low-light-level camera
Length of observation	5-10 min	5-0 min	Few minutes	Seconds	Seconds
Precision of detection	1-10 nm	5-20 nm	10-40 nm	20-50 nm	20-50 nm