Topic Introduction

Epidemiologic Considerations in Complex Disease Genetics

Adapted from Genetics of Complex Human Diseases (ed. Al-Chalabi and Almasy). CSHL Press, Cold Spring Harbor, NY, USA, 2009.

Abstract

Association studies are becoming an increasingly popular study design not only for testing of candidate genes, but also for genome-wide localization of loci influencing complex disease. This article covers some of the practical concerns in conducting large-scale association studies using epidemiologic samples.

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