Topic Introduction

Estimating Surface Area in Biological Structures

Adapted from Basic Stereology for Biologists and Neuroscientists by Mark J. West. CSHL Press, Cold Spring Harbor, NY, USA, 2012.

Abstract

Stereological estimates of surface have led to important insights into normal and pathological processes. This article describes the process of estimating surface area in biological structures. It includes a discussion of relationship equations for estimating surface and procedures for estimating surface area of components of organ systems. It also provides an example of estimation of the area of the pial surface of the human brain.

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