Table 2.
Caspase substrate databases and substrate prediction servers
| Name | URL | Laboratory | Substrate number | Species covered | Reference |
|---|---|---|---|---|---|
| CASBAH | http://bioinf.gen.tcd.ie/casbah/ | Seamus Martin | 777 | H, M, R, A, D, C, V | Luthi and Martin 2007 |
| CASVM | http://www.casbase.org/casvm/index.html | Shoba Ranganathan | 272 | H, V | Wee et al. 2007 |
| CasCleave | http://sunflower.kuicr.kyoto-u.ac.jp/~sjn/Cascleave/ | Jiangning Song | 370 | Song et al. 2010 | |
| CasPredictora | http://icb.usp.br/~farmaco/Jose/CaSpredictorfiles | Jose Ernesto Belizario | 160 | Garay-Malpartida et al. 2005 | |
| PMAP-CutDBb | http://www.proteolysis.org/proteases/ | Jeffrey Smith | H, M, R, A, D, C | Igarashi et al. 2009 | |
| MEROPSb | http://merops.sanger.ac.uk/index.shtml | Neil Rawlings & Alan Barret | H, M, R, A, D, C | Rawlings et al. 2012 |
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aDatabase closed, contact J.E. Belizario for further information.
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bA large protease and substrate database with large amounts of information on caspases and substrates from many species.
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H, human; M, mouse; R, rat; A, Arabidopsis; D, Drosophila; C, C. elegans; V, virus










