Protocol

Induction of Colon Cancer in Mice with 1,2-Dimethylhydrazine

  1. Christopher J. Kemp1
  1. Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109

    Abstract

    In this protocol, colon cancer is induced in mice through a series of injections with 1,2-dimethylhydrazine. Mice will develop primarily colon tumors starting at about 3 mo after the first injection. Tumors in the lung, uterus, and small intestine may also be seen, as well as lymphomas.

    Footnotes

    • ↵1 Correspondence: cjkemp{at}fhcrc.org

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    1. doi:10.1101/pdb.prot077453 Cold Spring Harb Protoc 2015: pdb.prot077453- © 2015 Cold Spring Harbor Laboratory Press
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