Induction of Colon Cancer in Mice with 1,2-Dimethylhydrazine
Abstract
In this protocol, colon cancer is induced in mice through a series of injections with 1,2-dimethylhydrazine. Mice will develop primarily colon tumors starting at about 3 mo after the first injection. Tumors in the lung, uterus, and small intestine may also be seen, as well as lymphomas.
Footnotes
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↵1 Correspondence: cjkemp{at}fhcrc.org
- © 2015 Cold Spring Harbor Laboratory Press
