Topic Introduction

The Nuclear Matrix: Fractionation Techniques and Analysis

  1. Dawn Coverley1
  1. 1Department of Biology, University of York, York YO10 5DD, United Kingdom
    • 2 Present address: Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, United Kingdom.

    Abstract

    The first descriptions of an insoluble nuclear structure appeared more than 70 years ago, but it is only in recent years that a sophisticated picture of its significance has begun to emerge. Here we introduce multiple methods for the study of the nuclear matrix.

    Footnotes

    • 3 Correspondence: rosemary.wilson{at}well.ox.ac.uk

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