Cover image

Fluorescent image of mitotic spindles assembled in cell-free Xenopus extract droplets. In this issue, John Oakey and Jesse Gatlin detail the use of multiphase microfluidic devices to encapsulate Xenopus sperm nuclei within egg extract droplets (doi: 10.1101/pdb.prot102913). Image taken by James Hazel, courtesy of the Gatlin laboratory.