Cover image

Olfactory bulb of larval Xenopus laevis (captured by multiphoton microscopy) with individual labeling of olfactory receptor neuron axons (cyan), a group of mitral/tufted cells (yellow), and cell bodies of the local olfactory bulb neuronal network (magenta). In this issue, Thomas Offner and colleagues provide a protocol for recording the activity of entire neuronal networks in X. laevis using genetically encoded or focally injected chemical calcium indicators in combination with multiphoton calcium imaging (doi: 10.1101/pdb.prot106815). Photograph courtesy of Thomas Offner.