Table 11.

Routes of injection for rabbits

Route Immunogen (form) Adjuvant Comments
Intraperitoneal Soluble or insoluble +/– If used for final boost, wait 5 d before fusion.
Subcutaneous Soluble or insoluble +/– Local response
Serum levels slower to increase
Intravenous Soluble No Freund's Poor for immunizing
Ionic detergent <0.2%
Nonionic detergent <0.5%
Salt <0.3 m
Urea <1 m
Intramuscular, intradermal, lymph node Soluble or insoluble No Freund's Good applications for experienced workers

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