Table 6.
Choice of adjuvant
| Adjuvant | Type | Advantages | Disadvantages |
|---|---|---|---|
| Freund's adjuvant | Water on oil | Increased surface area for antigen presentation | Chronic inflammation |
| Excellent immune stimulation | Can increase granulomas and abscesses | ||
| Ribi Adjuvant System | Oil on water | Induces good immune stimulation | Less potent |
| Metabolizable oil is less inflammatory. | Less depot effect | ||
| Hunter's TiterMax | Water on oil | Good immune stimulation | Less depot effect |
| Less inflammatory | |||
| Activates complement | |||
| ImmunEasy | Aqueous | No inflammation | No depot effect |
| Targets innate immune system | |||
| Aluminum hydroxide | Mineral salt | Less inflammation | No depot effect |
| Induces good memory | Weak immune stimulator | ||
| Nitrocellulose | Solid matrix | Slow release of antigen | Antigen is denatured, hard to implant. |
