Table 2.

Transgenic fly lines that can be used to detect biochemical mitochondrial changes in wing neurons

Tool	Mitochondrial measurements	Tool development	Initial use in Drosophila
5xUAS-mito-roGFP2-Grx1	Glutathione-specific redox reporter	Gutscher et al. 2008; Ostergaard et al. 2001	Albrecht et al. 2011
5xUAS-mito-roGFP2-Orp1	H₂O₂-specific redox reporter	Gutscher et al. 2009	Albrecht et al. 2011
20xUAS-mito-GCaMP5	Ca²⁺ levels	Dana et al. 2019; Nakai et al. 2001	Smith et al. 2019b
5xUAS-mitoTimer	Age/dynamics reporter	Terskikh et al. 2000	Laker et al. 2014
5xUAS-mitoQC	Mitophagy reporter	Allen et al. 2013	Lee et al. 2018
5xUAS-mito-keima	Mitophagy reporter	Katayama et al. 2011; Kogure et al. 2006	Lee et al. 2018
5xUAS-mito-Dendra2	Photo-convertible for dynamic studies	Gurskaya et al. 2006	Hwang et al. 2014
UAS-mito-PA-GFP	Photo-activatable for dynamic studies	Karbowski et al. 2004	Chowdhary et al. 2017