Analysis of complementarity-determining regions (CDRs) L3 and H3. (A) Distribution of CDR-L3 lengths (positions 107–116, left) and CDR-H3 lengths (positions 106–117, right) for the selected synthetic and natural antibodies (Abs). (B) Amino acid composition of CDR-L3 (positions 107–114, left) and CDR-H3 (positions 107–113, right) for the selected synthetic and natural Abs. The percent abundance within the CDR is shown for each amino acid, and the amino acids are ordered from the most to least abundant within the synthetic Abs.