Table

Table 1. Some key features of maturation of the tammar wallaby, Macropus eugenii, with respect to development of the brain, thyroid, and immune and reproductive systems

Days from birth General Brain Thyroid Immune system Reproductive system
−4 Scrotum and mammary primordia
0 Birth weight ~ 400 mg Neocortex of brain equivalent to 25-d sheep fetus or 12-d rat fetus
2 Testis cords develop
4 First axons from retinal ganglion cell layer cross to opposite side of brain via optic chiasm
5-6 Initial appearance of cortical plate Pouch primordia
8 Ovarian differentiation starts; Wolffian duct regression
10 Mullerian duct regression
10-15 Cortical plate complete throughout telencephalon Early immune responses start
25 Female germ cells start entry into meiosis
30 Thyroxine (T4) is at adult concentrations, triiodothyronine (T3) is much lower Prostate development starts
40-60 Phallus becomes sexually dimorphic
50 Germ cell numbers peak in female; most are in meiosis
60 Testicular descent complete
70 Mature pattern of eye innervation appears. Completion of six layers of adult cerebral cortex
100 Voluntarily releases teat
120 Four- to fivefold increase in T4 concentrations
120-150 Lymph nodes fully developed
125 Milk composition changes from high carbohydrate, low fat and protein to high fat and protein, low carbohydrate
140 Eyes open, underfur starts to appear
150 Capable of some degree of homeothermy T3 levels increase
160 Head first out of pouch, able to stand
170 Starts to nibble grass
180 Completely homeothermic Thyroid function complete; T4 levels decline to adult
190 First out of pouch; able to hop
196-252 Weaning
200 Full pelage
250 Out of pouch permanently
280-310 Females enter puberty
315-350 Fully independent: weight 1.6‐2.5.kg
570+ Males enter puberty
These data are derived from Tyndale-Biscoe and Janssens (1988), Renfree (1994a, 2006), Renfree et al. (1982), and Reynolds and Saunders (1988).
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  1. doi:10.1101/pdb.tab1emo137 Cold Spring Harb Protoc 2009: pdb.tab1emo137-

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