Schematic diagram of a phage antibody (not to scale). An antibody domain—most often a single-chain variable fragment (scFv) or an antigen-binding fragment (Fab)—is displayed on the surface of a virion (phage particle). The displayed antibody domain is exposed in the surrounding medium, where it can bind to an antigen. The virion's chromosome contains the coding sequence for the antibody domain it displays.
Figure 1.

Schematic diagram of a phage antibody (not to scale). An antibody domain—most often a single-chain variable fragment (scFv) or an antigen-binding fragment (Fab)—is displayed on the surface of a virion (phage particle). The displayed antibody domain is exposed in the surrounding medium, where it can bind to an antigen. The virion's chromosome contains the coding sequence for the antibody domain it displays.

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  1. Published in Advance October 22, 2025, doi: 10.1101/pdb.over107753 Cold Spring Harb Protoc 2026: pdb.over107753-
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